From the Picrust website:

PICRUSt (pronounced pie crust) is a bioinformatics software package 
designed to predict metagenome functional content from marker gene (e.g., 16S rRNA) 
surveys and full genomes.


Because PICRUSt is a Python package, it can be setup on Odyssey using a local Anaconda clone. It is a bit more complex than a simple pip install, though.

Setup a conda clone

Follow the instructions for setting up an Anaconda clone on Odyssey, if you don't already have one.

$ module load python/2.7.14-fasrc01
$ conda create -n ody --clone $PYTHON_HOME
$ source activate ody
(ody) $ python
Python 2.7.14 |Anaconda, Inc.| (default, Oct 16 2017, 17:29:19)
[GCC 7.2.0] on linux2
Type "help", "copyright", "credits" or "license" for more information.

Setup h5py

As noted in the instructions for setting up h5py on Odyssey, h5py can be pip installed into your conda clone, but you should choose a module for HDF5 based on your likely compiler and MPI library stack.

$ source activate ody
discarding /n/sw/fasrcsw/apps/Core/Anaconda/2.5.0-fasrc01/x/bin from PATH
prepending /n/home_rc/akitzmiller/.conda/envs/ody/bin to PATH
(ody) $ module load hdf5/1.8.12-fasrc08
(ody) $ pip install h5py
Collecting h5py
  Downloading h5py-2.7.0-cp27-cp27mu-manylinux1_x86_64.whl (4.3MB)
    100% |████████████████████████████████| 4.4MB 140kB/s 
Installing collected packages: h5py
Successfully installed h5py-2.7.0
(ody) $

Install biom-format

This can be installed with a simple pip install with your clone activated

(ody) $ pip install biom-format==2.1.5

Install PICRUSt

This must be installed from an downloaded archive. The archive need not be unpacked. PyCogent will also be installed.

(ody) $ wget
--2017-07-10 13:57:57--
Connecting to||:443... connected.
Saving to: “picrust-1.1.1.tar.gz”
2017-07-10 13:57:58 (17.0 MB/s) - “picrust-1.1.1.tar.gz” saved [10826010/10826010]

(ody) $ pip install picrust-1.1.1.tar.gz 
Processing ./picrust-1.1.1.tar.gz
Collecting cogent==1.5.3 (from PICRUSt==1.1.1)
  Downloading cogent-1.5.3.tgz (3.4MB)
    100% |████████████████████████████████| 3.4MB 182kB/s 
Building wheels for collected packages: PICRUSt, cogent
  Running bdist_wheel for PICRUSt ... done
  Running bdist_wheel for cogent ... done
Successfully built PICRUSt cogent
Installing collected packages: cogent, PICRUSt
  Found existing installation: cogent 1.9
    Uninstalling cogent-1.9:
      Successfully uninstalled cogent-1.9
Successfully installed PICRUSt-1.1.1 cogent-1.5.3

(ody) $ --help
Usage: [options] {-t/--input_tree INPUT_TREE -i/--input_trait_table INPUT_TRAIT_TABLE}

[] indicates optional input (order unimportant)
{} indicates required input (order unimportant)